| Name | Benzamidine hydrochloride |
| Synonyms | Benzamidine HCL Benzamidine hydrochl benzamidiniumchloride benzenecarboximidamide benzamidinium chloride Benzamidine hydrochloride BenziMidaMide hydrochloride amidinobenzenehydrochloride benzamidine hydroxychloride Benzamidine hydrochloride solution benzenecarboximidamide hydrochloride hydrate 2-hydroxybenzene-1-carboxiMidaMide hydrochloride |
| CAS | 1670-14-0 143504-23-8 |
| EINECS | 216-795-4 |
| InChI | InChI=1/C7H8N2.ClH.H2O/c8-7(9)6-4-2-1-3-5-6;;/h1-5H,(H3,8,9);1H;1H2 |
| InChIKey | LZCZIHQBSCVGRD-UHFFFAOYSA-N |
| Molecular Formula | C7H9ClN2 |
| Molar Mass | 156.61 |
| Melting Point | 86-88°C(lit.) |
| Boling Point | 332.9°C at 760 mmHg |
| Flash Point | 155.1°C |
| Water Solubility | soluble |
| Solubility | Insoluble in water. |
| Vapor Presure | 5.63E-05mmHg at 25°C |
| Appearance | Crystalline powder |
| Color | White to off-white |
| BRN | 3594959 |
| PH | 4.0 to 6.5(50g/L, 25 ℃) |
| Storage Condition | 2-8°C |
| Stability | Stable for 2 years from date of purchase as supplied. Solutions are not stable and must be prepared fresh daily |
| MDL | MFCD00013025 |
| Use | For biochemical research |
| In vitro study | Benzamidine hydrochloride has weak inhibition for tPA and thrombin, with K i s of 750 µM and 320 µM, respectively. |
| Hazard Symbols | Xi - Irritant![]() |
| Risk Codes | 36/37/38 - Irritating to eyes, respiratory system and skin. |
| Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39 - Wear suitable gloves and eye/face protection S36 - Wear suitable protective clothing. |
| WGK Germany | 3 |
| RTECS | CV6260000 |
| FLUKA BRAND F CODES | 3-21 |
| HS Code | 29252900 |
| Reference Show more | 1. [IF=7.514] Yeming Chen et al."Endopeptidases, exopeptidases, and glutamate decarboxylase in soybean water extract and their in vitro activity."Food Chem. 2021 Oct;360:130026 |
| EPA chemical information | Information provided by: ofmpub.epa.gov (external link) |
| Biological activity | Benzamidine hydrochloride is a reversible, competitive trypsin-like serine protease (trypsin-like serine proteases) inhibitor, The Ki values of uPA, trypsin, tryptase and Xa factor are 97 µM, 21 µM, 20 µM and 110 µM, respectively. |
| target | Ki: 97 µM (uPA), 21 µM (trypsin), 20 µM (tryptase), 110 µM (factor Xa) |
| use | for biochemical research |
| category | toxic substances |
| toxicity classification | poisoning |
| acute toxicity | abdominal cavity-mouse LD50: 580 mg/kg |
| flammability hazard characteristics | combustible; combustion produces toxic nitrogen oxides, chloride and hydrogen chloride fumes |
| storage and transportation characteristics | ventilation and low temperature drying |
| fire extinguishing agent | dry powder, foam, sand, carbon dioxide, mist water |